LAY LANGUAGE
Glioblastoma is a type of brain tumor that is almost always lethal. Traditional cancer treatments like chemotherapy and immunotherapy are often ineffective on glioblastoma. Purdue University researchers are developing and validating a new treatment for glioblastoma.
PROBLEM
Glioblastoma is a type of brain cancer that is almost always lethal; median survival time is 14 months. Traditional cancer treatments like chemotherapy and immunotherapy have limited to no effect on glioblastoma.
SOLUTION
Purdue University researchers are developing a novel treatment for glioblastoma. Traditional treatments use cells taken from a patient’s blood and returned to the same patient. The Purdue treatment sources pluripotent stem cells from a source other than the patient, genetically engineers them into natural killer cells and gives those to the patient.
The Purdue team tested its treatment by conducting animal studies with mice bearing human brain tumors, which were treated by direct injection of the newly engineered immune cells. Studies showed the Purdue treatment did very well in targeting and completely eliminating the growth of the tumors.
PRIMARY INVESTIGATOR
Sandro Matosevic, College of Pharmacy
IN THE MEDIA
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LICENSING CONTACTS
Email: otcip@prf.org
MEDIA CONTACT
Email: Steve Martin // sgmartin@prf.org
