Promising research from Purdue offers innovation, hope for cancer treatment 

October 3, 2024

Research is at the heart of innovative solutions to cancer.

Here are just a few Boilermaker researchers who have moved their research from lab to life with the help of the Purdue Innovates Office of Technology Commercialization:

Zhong-Yin Zhang

Current immunotherapy approaches are effective in only 15% of the patient population. Innovations like Zhang’s TC-PTP offer a novel alternative approach that degrades an enzyme found in cancer cells, alerting the immune system to the presence of tumor cells.

Yoon Yeo

Yeo’s nanoparticles slowly release drugs that induce immunogenic cell death, or ICD, in tumors. ICD results in a regulated activation of the immune response which is helpful since many cancer patients do not have powerful immune cells to fight tumors on their own.

Herman Sintim

AML is a cancer that begins in bone marrow and sometimes metastasizes to the central nervous system, liver, lymph nodes, spleen, and testicles. Sintim’s compound can treat AML with a 3D atomic structure perfectly designed to address the challenges of drug resistance.

Sandro Matosevic

Glioblastoma brain tumors are almost always lethal — with a median survival time of 14 months — since traditional methods used against other cancers are often ineffective. Matosevic is leading a team developing an immunotherapy based on novel, genetically engineered immune cells.

Phil Low

Innovation starts in the lab, but the widespread benefits and real-world application really can’t begin until commercialization. How does a cancer-fighting discovery go from research to a product being used in a hospital for a loved one’s life-saving treatment? Low is just the expert to demystify the process.

Media contact: Polly Barks, phbarks@prf.org

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