National Diabetes Month: Purdue-connected startup Adipo Therapeutics

October 31, 2023
While weight loss can be achieved through decreasing calorie intake and/or increasing energy expenditure, the newer therapies on the market today are focused only on appetite suppression to reduce a person’s daily caloric intake. There is a need for new products that work to increase energy expenditure without limiting calorie intake.

Karen Wurster, MBA

CEO of Adipo Therapeutics

November is National Diabetes Month, bringing awareness to a disease that affects about 37 million American adults and youth according to the National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes occurs when a person’s blood sugar is too high; it can cause damage to the eyes, heart, kidneys, and nerves and is associated with certain cancers.

Adipo Therapeutics and its innovate technology

Adipo Therapeutics is a biotechnology startup whose technology increases the amount of energy-burning, metabolically beneficial brown fat in the body by converting energy-storing white fat. Research has shown a correlation between higher levels of brown fat with lower odds of type 2 diabetes and obesity along with congestive heart failure, hypertension and other conditions.

“The event showcased the vast range of industry expertise and startup innovation coming through the Purdue ecosystem,” said Madison Sowards, community manager, Ventures, Purdue Innovates. “Entrepreneurs understand the value in their Purdue connections. Participants traveled from every corner of the United States – California, Florida, Massachusetts and Texas – along with those based Indiana.”

Leaders delivered three-minute pitches then engaged with attendees at their expo booths. The participants and their companies were:

  • Meng Deng and Keith Johns, Adipo Therapeutics. Adipo Therapeutics is a late-stage pre-clinical biopharmaceutical company developing a treatment to combat the dual epidemics of obesity and type 2 diabetes. Notch inhibition along with nanoparticle technology are used to increase energy expenditure by converting energy-storing white fat into energy-burning, metabolically beneficial brown fat. Adipo is based in Indiana.

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